Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5318469 | 0.91 | SMN1; SMN2 (0.36) | POLBSMN1; SMN2RAB9ALMNAMAPK1 | |
| SCHEMBL5314390 | 0.91 | LMNA (0.36) | POLBSMN1; SMN2RAB9ALMNAMAPK1 | |
| SCHEMBL5316133 | 0.86 | POLB (0.39) | POLBRAB9ALMNAMAPTMEN1 | |
| SCHEMBL5315021 | 0.80 | HTT (0.37) | POLBSMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL5313356 | 0.80 | KMT2A (0.38) | POLBSMN1; SMN2RAB9ALMNAMAPT | |
| SCHEMBL5315683 | 0.79 | KMT2A (0.47) | POLBSMN1; SMN2RAB9ALMNANPC1 | |
| SCHEMBL5316805 | 0.79 | MEN1 (0.34) | POLBMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL5314189 | 0.78 | TLR7 (0.37) | POLBSMN1; SMN2RAB9ALMNAMAPT | |
| SCHEMBL14494201 | 0.78 | RORC (0.38) | — | |
| SCHEMBL5313867 | 0.78 | MAPT (0.38) | POLBSMN1; SMN2RAB9ALMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007066496-A1 | BENZOYLUREA COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-14 | — | — | WO | disclosed |