Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.46 |
| ▸ | RELA | Q04206 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5313369 | 0.83 | PTGDR2 (0.74) | PTGDR2 | |
| SCHEMBL5315782 | 0.79 | PTGDR2 (0.70) | PTGDR2MAPTRAB9ANPC1HTT | |
| SCHEMBL1992171 | 0.77 | MAPT (0.71) | PTGDR2MEN1KMT2AMAPTRAB9A | |
| SCHEMBL5332229 | 0.77 | MEN1 (0.45) | PTGDR2MEN1KMT2AMAPTRAB9A | |
| SCHEMBL1993758 | 0.76 | RAB9A (0.73) | PTGDR2MEN1KMT2AMAPTRAB9A | |
| SCHEMBL1996282 | 0.72 | MEN1 (0.72) | PTGDR2MEN1KMT2AMAPTRAB9A | |
| SCHEMBL5319902 | 0.72 | LDHA (0.43) | PTGDR2 | |
| SCHEMBL30512088 | 0.70 | ALKBH5 (0.72) | PTGDR2MAPTRAB9ANPC1HTT | |
| SCHEMBL1993265 | 0.70 | PTGDR2 (0.77) | PTGDR2 | |
| SCHEMBL1997356 | 0.69 | RAB9A (0.73) | PTGDR2MEN1KMT2AMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007062678-A1 | PHENOXYACETIC ACID DERIVATIVES AS CRTH2 RECEPTOR LIGANDS | 7TM PHARMA A/S (DK) | 2007-06-07 | — | — | WO | disclosed |