SCHEMBL1449565

SCHEMBL1449565

NCCOC(=O)c1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.70
LMNA P02545 2/20 0.66
MAPK1 P28482 1/20 0.57
HIF1A Q16665 1/20 0.57
SLC6A2 P23975 1/20 0.57
SLC6A3 Q01959 1/20 0.57
KMT2A Q03164 1/20 0.57
ALDH1A1 P00352 2/20 0.55
NPC1 O15118 1/20 0.54
RAB9A P51151 1/20 0.54
KDM4E B2RXH2 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
GAA P10253 1/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
F2 P00734 1/20 0.52
TSHR P16473 2/20 0.52
ESR1 P03372 1/20 0.51
ESR2 Q92731 1/20 0.51
IDO1 P14902 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9114435 0.98 TDP1 (0.68) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL30823716 0.98 TDP1 (0.68) TDP1LMNAMAPK1HIF1ASLC6A2
Benzoic Acid SCHEMBL28667948 0.94 TDP1 (0.63) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL11352210 0.93 TDP1 (0.61) TDP1LMNAMAPK1HIF1ASLC6A2
Trifluoroacetic Acid SCHEMBL28490953 0.89 TDP1 (0.58) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL7902687 0.89 TDP1 (0.61) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL14369808 0.89 KDM4E (0.65) TDP1LMNAMAPK1HIF1AALDH1A1
SCHEMBL7292310 0.88 TDP1 (0.78) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL137486 0.87 TDP1 (0.83) TDP1LMNAMAPK1HIF1ASLC6A2
SCHEMBL1410185 0.86 TDP1 (0.81) TDP1LMNAMAPK1HIF1ASLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 206 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230148641-A1 FLAVOR COMPOSITION FIRMENICH SA (CH) 2023-05-18 US claimed
EP-4125427-A1 FLAVOR COMPOSITION Firmenich SA (CH) 2023-02-08 EP claimed
CN-115279206-A Flavor composition 弗门尼舍有限公司 2022-11-01 CN claimed
WO-2021198199-A1 FLAVOR COMPOSITION FIRMENICH SA (CH) 2021-10-07 WO claimed
CN-111909044-A Synthesis method of 2- (alkylamino) ethyl benzoate compound 南京爱德程医药科技有限公司 2020-11-10 CN claimed
CN-110495410-A A kind of little yellow croaker frozen sperm and Larimichthys crocea hybridizing propagation process ZHEJIANG ACAD AGRICULTURAL SCI 2019-11-26 CN claimed
EP-2888208-B1 MULTI-PURPOSE MORTAR OR CEMENT COMPOSITIONS FOR CONSTRUCTION APPLICATIONS SIKA TECH AG (CH) 2018-01-31 EP claimed
CN-106220921-B A kind of brake ribbon based on modified composite fiber and preparation method thereof 新昌县城南乡量新机械厂 2017-11-24 CN claimed
CN-107254349-A A kind of preparation method of rolling mill compound 常州豫春化工有限公司 2017-10-17 CN claimed
CN-106637222-A Preparation method of stainless steel polishing solution with reduced re-rusting rate 戴琪 2017-05-10 CN claimed
US-20150203407-A1 MULTI-PURPOSE MORTAR OR CEMENT COMPOSITIONS FOR CONSTRUCTION APPLICATIONS SIKA TECHNOLOGY AG (CH) 2015-07-23 US claimed
EP-2888208-A1 MULTI-PURPOSE MORTAR OR CEMENT COMPOSITIONS FOR CONSTRUCTION APPLICATIONS Sika Technology AG (CH) 2015-07-01 EP claimed
WO-2014029658-A1 MULTI-PURPOSE MORTAR OR CEMENT COMPOSITIONS FOR CONSTRUCTION APPLICATIONS SIKA TECHNOLOGY AG (CH) 2014-02-27 WO claimed
US-20090062521-A1 AMIDITE FOR SYNTHESIZING MODIFIED NUCLEIC ACID AND METHOD FOR SYNTHESIZING MODIFIED NUCLEIC ACID FUJITSU LIMITED (JP) 2009-03-05 US claimed
US-6420470-B1 PLASTIC RESIN FILM WITH PROTECTIVE ENCLOSURES CORTEC CORPORATION 2002-07-16 US claimed
US-5972862-A COMPRISING A FLUORINE-CONTAINING COMPOUND, A WATER-SOLUBLE OR WATER-MISCIBLE ORGANIC SOLVENT, AN ORGANIC ACID, AND A QUATERNARY AMMONIUM SALT MITSUBISHI GAS CHEMICAL (JP) 1999-10-26 US claimed
EP-0543713-B1 Ethanolamine benzoate derivatives, process for their preparation and pharmaceutical compositions containing them ADIR (FR) 1995-02-22 EP claimed
US-5266718-A Antidiabetic agents ADIR ET COMPAGNIE (FR) 1993-11-30 US claimed
US-5266591-A For treatment of abnormal metabolism ADIR ET COMPAGNIE (FR) 1993-11-30 US claimed
EP-0200024-A2 3-Cyano-pyridines, process for their preparation and their pharmaceutical use ARZNEIMITTELWERK DRESDEN GmbH (DE) 1986-11-05 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090062521-A1 AMIDITE FOR SYNTHESIZING MODIFIED NUCLEIC ACID AND METHOD FOR SYNTHESIZING MODIFIED NUCLEIC ACID NSUN2, RNMT, ADAR TDP1 387/4885LMNA 93/4885MAPK1 2656/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.