Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8924696 | 0.87 | EP300 (0.46) | EP300ALDH1A1GAAKDM4ETP53 | |
| SCHEMBL8914807 | 0.78 | SCN9A (0.39) | EP300ALDH1A1KDM4E | |
| SCHEMBL7275181 | 0.76 | KDM4E (0.41) | EP300ALDH1A1KDM4EPOLBKMT2A | |
| Hydrochloric Acid SCHEMBL7283867 | 0.75 | F10 (0.48) | — | |
| SCHEMBL38659205 | 0.71 | HDAC1 (0.42) | EP300PKMKMT2AL3MBTL1 | |
| SCHEMBL12275459 | 0.71 | FFAR4 (0.48) | ALDH1A1KDM4EPOLBKMT2ACYP3A4 | |
| SCHEMBL7274147 | 0.68 | PRMT5 (0.44) | EP300ALDH1A1KDM4EPOLBKMT2A | |
| SCHEMBL8913757 | 0.67 | LMNA (0.45) | PKMALDH1A1KDM4ELMNAPOLB | |
| Hydrochloric Acid SCHEMBL7274970 | 0.67 | ITGB3 (0.46) | — | |
| SCHEMBL20343472 | 0.66 | ADAM17 (0.45) | ALDH1A1GAAHPGDPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007066784-A2 | DIARYLETHER DERIVATIVES AS ANTITUMOR AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-06-14 | — | — | WO | disclosed |