SCHEMBL14496830

SCHEMBL14496830

Cc1ccc(CI)nc1Cl

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20110642 0.79 ALDH1A1 (0.35) ALDH1A1
SCHEMBL3938309 0.77 CCR1 (0.48) ALDH1A1
Hydrochloric Acid SCHEMBL6588208 0.73 NOS3 (0.37) ALDH1A1
SCHEMBL4664505 0.72 CYP1A2 (0.33) ALDH1A1
SCHEMBL2353586 0.71
SCHEMBL27951352 0.71 ALDH1A1 (0.41) ALDH1A1
SCHEMBL940010 0.70
SCHEMBL266594 0.70
SCHEMBL30019312 0.70
SCHEMBL29670201 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007066784-A2 DIARYLETHER DERIVATIVES AS ANTITUMOR AGENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-06-14 WO disclosed