Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CHKA | P35790 | 3/20 | 0.41 |
| ▸ | APP | P05067 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16707224 | 0.80 | ALDH1A1 (0.52) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL4068305 | 0.78 | CALM1 (0.56) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL14499021 | 0.78 | CYP1A2 (0.46) | ALDH1A1CYP3A4ALOX15CHKAHRH3 | |
| SCHEMBL4405018 | 0.76 | ALDH1A1 (0.70) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL9725762 | 0.76 | ESR1 (0.52) | ALDH1A1CYP3A4TDP1CALM1HSD17B10 | |
| SCHEMBL19120785 | 0.76 | KMT2A (0.50) | MAPK1MAOB | |
| SCHEMBL92354 | 0.75 | CA1 (0.44) | ALDH1A1TSHRALOX15HSD17B10MAOA | |
| SCHEMBL14524153 | 0.74 | TSHR (0.50) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL14499023 | 0.74 | TAAR1 (0.53) | ALDH1A1CALM1MAOBHTT | |
| SCHEMBL11265024 | 0.74 | SLC6A4 (0.58) | ALDH1A1TSHRMAPK1ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7226950-B2 | Sodium channel modulators | THERAVANCE, INC. (US) | 2007-06-05 | — | — | US | disclosed |