Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 3/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11652085 | 0.80 | CYP1A2 (0.49) | TP53CYP1A2LIMK1ESR1ESR2 | |
| SCHEMBL4816590 | 0.78 | PDCD1 (0.33) | PDCD1CD274 | |
| SCHEMBL9770710 | 0.76 | KDM4E (0.36) | TP53CYP1A2LIMK1 | |
| SCHEMBL4655427 | 0.70 | CD274 (0.36) | CD274LIMK1IDO1 | |
| SCHEMBL14016124 | 0.70 | ALDH1A1 (0.37) | LIMK1 | |
| SCHEMBL14499144 | 0.69 | RXRA (0.41) | IDO1TDO2ESR1ESR2 | |
| SCHEMBL13199168 | 0.67 | PDCD1 (0.50) | PDCD1CD274 | |
| SCHEMBL14016126 | 0.67 | ALDH1A1 (0.40) | LIMK1 | |
| SCHEMBL4654421 | 0.67 | RXRA (0.39) | CD274CYP1A2ESR1 | |
| SCHEMBL9078629 | 0.67 | TP53 (0.39) | TP53CYP1A2RARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7235699-B2 | Alkoxy-substituted indanes and the production thereof | SYMRISE GMBH & CO. KG (DE) | 2007-06-26 | — | — | US | disclosed |