Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11652085 | 0.80 | CYP1A2 (0.49) | LIMK1CYP1A2HTR2AHTR2CTP53 | |
| SCHEMBL4655427 | 0.77 | CD274 (0.36) | ALDH1A1LIMK1HTR2AHTR2CHTR2B | |
| SCHEMBL25027774 | 0.77 | CD44 (0.38) | KDM4EALDH1A1HPGDLIMK1CYP1A2 | |
| SCHEMBL14499142 | 0.76 | PDCD1 (0.36) | LIMK1CYP1A2TP53 | |
| SCHEMBL9629668 | 0.73 | BCL2L1 (0.39) | ALDH1A1LIMK1 | |
| SCHEMBL14016124 | 0.73 | ALDH1A1 (0.37) | KDM4EALDH1A1HPGDLIMK1POLB | |
| SCHEMBL9770690 | 0.71 | ALDH1A1 (0.40) | KDM4EALDH1A1HPGDCYP1A2POLB | |
| SCHEMBL4654421 | 0.70 | RXRA (0.39) | CYP1A2 | |
| SCHEMBL14016126 | 0.70 | ALDH1A1 (0.40) | ALDH1A1LIMK1HTR2C | |
| SCHEMBL9770701 | 0.70 | ALDH1A1 (0.32) | ALDH1A1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987261-A | Diaminoindane derivatives | MITSUI TOATSU CHEMICALS, INC. (JP) | 1991-01-22 | — | — | US | disclosed |