Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 3/20 | 0.46 |
| ▸ | CTSA | P10619 | 1/20 | 0.46 |
| ▸ | PPIB | P23284 | 1/20 | 0.46 |
| ▸ | PPIA | P62937 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16945902 | 0.87 | PTGS2 (0.46) | MCHR1PPARDCTSAPPIBPPIA | |
| SCHEMBL13098163 | 0.86 | MCHR1 (0.51) | MCHR1CTSAPPIBPPIAMEN1 | |
| SCHEMBL8302095 | 0.86 | GPR3 (0.44) | PPARDFFAR1FFAR4CA12CA9 | |
| SCHEMBL12989267 | 0.85 | PDGFRB (0.44) | MEN1ALDH1A1KMT2APDGFRBPDGFRA | |
| SCHEMBL21615667 | 0.83 | CYP17A1 (0.50) | MCHR1PPARDCTSAPPIBPPIA | |
| SCHEMBL1912033 | 0.82 | DYRK1A (0.52) | MEN1ALDH1A1KMT2APDGFRBPDGFRA | |
| SCHEMBL15342387 | 0.82 | DYRK1A (0.52) | MEN1ALDH1A1KMT2APDGFRBPDGFRA | |
| SCHEMBL12890142 | 0.82 | ALDH1A1 (0.51) | MCHR1CTSAPPIBPPIAMEN1 | |
| SCHEMBL12326161 | 0.80 | PDGFRB (0.58) | ALDH1A1PDGFRBPDGFRAFFAR1MAPT | |
| SCHEMBL13580999 | 0.80 | CHRNA7 (0.44) | MCHR1CTSAPPIBPPIAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070149570-A1 | Piperidine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149570-A1 | Piperidine derivative and use thereof | TACR1, OPRL1, TRPV1 | MCHR1 363/4885PPARD 1246/4885CTSA 891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.