Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NQO1 | P15559 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.48 |
| ▸ | CDK4 | P11802 | 2/20 | 0.48 |
| ▸ | CCND1 | P24385 | 2/20 | 0.48 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.48 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.48 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.48 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.48 |
| ▸ | PRKCA | P17252 | 4/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | PRKCG | P05129 | 1/20 | 0.46 |
| ▸ | PRKCB | P05771 | 1/20 | 0.46 |
| ▸ | PRKACA | P17612 | 1/20 | 0.46 |
| ▸ | PRKACG | P22612 | 1/20 | 0.46 |
| ▸ | PRKACB | P22694 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8324352 | 0.81 | NQO1 (0.74) | MEN1KMT2ANQO1ROCK2CDK4 | |
| SCHEMBL14499964 | 0.77 | ROCK2 (0.57) | MEN1KMT2ANQO1ROCK2CDK4 | |
| SCHEMBL14525822 | 0.74 | CDK4 (0.58) | MEN1KMT2ANQO1ROCK2CDK4 | |
| SCHEMBL14041196 | 0.73 | NQO1 (0.43) | MEN1KMT2ANQO1ROCK2CDK4 | |
| SCHEMBL8324051 | 0.72 | NQO1 (0.51) | MEN1KMT2ANQO1ROCK2CDK4 | |
| SCHEMBL2644855 | 0.70 | KDM4E (0.57) | MEN1KMT2AKDM4EHKDC1MAPT | |
| SCHEMBL8354419 | 0.70 | NQO1 (0.48) | MEN1KMT2ANQO1ROCK2CDK4 | |
| SCHEMBL8335725 | 0.70 | PDGFRB (0.61) | NQO1ROCK2CDK4CCND1CCNE2 | |
| SCHEMBL2644150 | 0.69 | KDM4E (0.66) | MEN1KMT2AKDM4EHKDC1RAB9A | |
| SCHEMBL30296389 | 0.69 | KDM4E (0.66) | MEN1KMT2AKDM4EHKDC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070149481-A1 | N,n-bridged, nitrogen-substituted carbacyclic indolocarbazoles as protein kinase inhibitors | NAD AG (DE) | 2007-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149481-A1 | N,n-bridged, nitrogen-substituted carbacyclic indolocarbazoles as protein kinase inhibitors | NIM1K, TNNI3K, MAP3K15 | MEN1 1324/4885KMT2A 1925/4885NQO1 1343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.