Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.74 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.55 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.55 |
| ▸ | CDK4 | P11802 | 2/20 | 0.55 |
| ▸ | CCND1 | P24385 | 2/20 | 0.55 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.55 |
| ▸ | CDK2 | P24941 | 2/20 | 0.55 |
| ▸ | CAMK2B | Q13554 | 2/20 | 0.55 |
| ▸ | CAMK2G | Q13555 | 2/20 | 0.55 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.55 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | PRKCA | P17252 | 3/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CMA1 | P23946 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8335725 | 0.88 | PDGFRB (0.61) | NQO1ROCK2CCNE2CDK4CCND1 | |
| SCHEMBL8313203 | 0.86 | NQO1 (1.00) | NQO1ROCK2CCNE2CDK4CCND1 | |
| SCHEMBL14499964 | 0.83 | ROCK2 (0.57) | NQO1ROCK2CCNE2CDK4CCND1 | |
| SCHEMBL5431717 | 0.83 | NQO1 (0.57) | NQO1ROCK2CCNE2CDK4CCND1 | |
| SCHEMBL8324051 | 0.82 | NQO1 (0.51) | NQO1ROCK2CCNE2CDK4CCND1 | |
| SCHEMBL14499962 | 0.81 | MEN1 (0.50) | NQO1ROCK2CCNE2CDK4CCND1 | |
| SCHEMBL8354419 | 0.80 | NQO1 (0.48) | NQO1ROCK2CCNE2CDK4CCND1 | |
| SCHEMBL8354277 | 0.78 | NQO1 (0.46) | NQO1ROCK2CCNE2CDK4CCND1 | |
| SCHEMBL8318378 | 0.74 | NQO1 (0.68) | NQO1CCNE2CDK4CCND1CCNE1 | |
| SCHEMBL14708720 | 0.74 | NQO1 (0.64) | NQO1ROCK2CCNE2CDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070149481-A1 | N,n-bridged, nitrogen-substituted carbacyclic indolocarbazoles as protein kinase inhibitors | NAD AG (DE) | 2007-06-28 | — | — | US | disclosed |
| US-20070149481-A1 | N,n-bridged, nitrogen-substituted carbacyclic indolocarbazoles as protein kinase inhibitors | NAD AG (DE) | 2007-06-28 | — | — | US | disclosed |
| WO-2004048384-A1 | N,N-BRIDGED, NITROGEN-SUBSTITUTED CARBACYCLIC INDOLOCARBAZOLES AS PROTEIN KINASE INHIBITORS | NAD AG (DE) | 2004-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149481-A1 | N,n-bridged, nitrogen-substituted carbacyclic indolocarbazoles as protein kinase inhibitors | NIM1K, TNNI3K, MAP3K15 | NQO1 1343/4885ROCK2 243/4885CCNE2 2436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.