Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 9/20 | 0.58 |
| ▸ | CCND1 | P24385 | 9/20 | 0.58 |
| ▸ | PRKCA | P17252 | 6/20 | 0.58 |
| ▸ | PRKACA | P17612 | 4/20 | 0.58 |
| ▸ | PRKACG | P22612 | 4/20 | 0.58 |
| ▸ | PRKACB | P22694 | 4/20 | 0.58 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.58 |
| ▸ | PRKCG | P05129 | 3/20 | 0.58 |
| ▸ | PRKCB | P05771 | 3/20 | 0.58 |
| ▸ | PRKCH | P24723 | 3/20 | 0.58 |
| ▸ | PRKCI | P41743 | 3/20 | 0.58 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.58 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.58 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.58 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.58 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.58 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.51 |
| ▸ | CAMK2B | Q13554 | 7/20 | 0.50 |
| ▸ | CAMK2G | Q13555 | 7/20 | 0.50 |
| ▸ | CAMK2D | Q13557 | 7/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14499962 | 0.74 | MEN1 (0.50) | CDK4CCND1PRKCAPRKACAPRKACG | |
| SCHEMBL14525823 | 0.73 | ROCK2 (0.70) | CDK4CCND1PRKCAPRKACAPRKACG | |
| SCHEMBL9196626 | 0.73 | CDK4 (1.00) | CDK4CCND1PRKCAPRKACAPRKACG | |
| SCHEMBL8317372 | 0.73 | PRKCA (1.00) | CDK4CCND1PRKCAPRKACAPRKACG | |
| SCHEMBL5438544 | 0.70 | PRKCA (0.71) | CDK4CCND1PRKCAPRKACAPRKACG | |
| SCHEMBL8318191 | 0.68 | PRKCA (0.67) | CDK4CCND1PRKCAPRKACAPRKACG | |
| Staurosporine Aglycon SCHEMBL29406635 | 0.68 | CDK4 (1.00) | CDK4CCND1PRKCAPRKACAPRKACG | |
| Staurosporine Aglycon SCHEMBL8124103 | 0.68 | CDK4 (1.00) | CDK4CCND1PRKCAPRKACAPRKACG | |
| Staurosporine Aglycon SCHEMBL30530825 | 0.68 | CDK4 (1.00) | CDK4CCND1PRKCAPRKACAPRKACG | |
| SCHEMBL9201406 | 0.65 | ROCK2 (0.64) | CDK4CCND1PRKCAPRKACAPRKACG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070149481-A1 | N,n-bridged, nitrogen-substituted carbacyclic indolocarbazoles as protein kinase inhibitors | NAD AG (DE) | 2007-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149481-A1 | N,n-bridged, nitrogen-substituted carbacyclic indolocarbazoles as protein kinase inhibitors | NIM1K, TNNI3K, MAP3K15 | CDK4 197/4885CCND1 902/4885PRKCA 84/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.