Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9196237 | 0.81 | HPGD (0.57) | KMT2AMAPTHPGDALDH1A1LMNA | |
| SCHEMBL23773682 | 0.80 | ALDH1A1 (0.44) | KMT2AMAPTHPGDALDH1A1LMNA | |
| SCHEMBL6164008 | 0.76 | HPGD (0.62) | KMT2AMAPTHPGDALDH1A1LMNA | |
| SCHEMBL10795656 | 0.75 | ALDH1A1 (0.57) | KMT2AMAPTHPGDALDH1A1LMNA | |
| SCHEMBL14501327 | 0.71 | KMT2A (0.47) | KMT2AMAPTHPGDALDH1A1LMNA | |
| SCHEMBL25440299 | 0.70 | KMT2A (0.76) | KMT2AMAPTHPGDALDH1A1LMNA | |
| SCHEMBL25440183 | 0.69 | MAPT (0.78) | KMT2AMAPTHPGDALDH1A1LMNA | |
| SCHEMBL25440072 | 0.69 | KMT2A (1.00) | KMT2AMAPTHPGDALDH1A1LMNA | |
| SCHEMBL20324682 | 0.69 | ALDH1A1 (0.50) | KMT2AMAPTHPGDALDH1A1LMNA | |
| SCHEMBL10795663 | 0.68 | TSHR (0.54) | KMT2AMAPTHPGDALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223795-B2 | Modified peptide derivatives and methods of use thereof | CYCLACEL LIMITED (GB) | 2007-05-29 | — | — | US | disclosed |
| US-7223795-B2 | Modified peptide derivatives and methods of use thereof | CYCLACEL LIMITED (GB) | 2007-05-29 | — | — | US | disclosed |