Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GBA1 | P04062 | 1/20 | 0.48 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14503163 | 1.00 | PTGS2 (0.57) | PTGS2LMNASMN1; SMN2HTTMAPT | |
| SCHEMBL14503676 | 0.94 | PTGS2 (0.52) | PTGS2LMNASMN1; SMN2HTTMAPT | |
| SCHEMBL14503548 | 0.94 | PTGS2 (0.53) | PTGS2LMNASMN1; SMN2HTTMAPT | |
| SCHEMBL14503642 | 0.93 | PTGS2 (0.53) | PTGS2LMNASMN1; SMN2HTTMAPT | |
| SCHEMBL14503628 | 0.92 | MAPT (0.49) | PTGS2LMNASMN1; SMN2HTTMAPT | |
| SCHEMBL14503664 | 0.92 | PTGS2 (0.49) | PTGS2LMNASMN1; SMN2HTTMAPT | |
| SCHEMBL14503398 | 0.92 | LMNA (0.58) | PTGS2LMNASMN1; SMN2HTTMAPT | |
| SCHEMBL14503227 | 0.91 | PTGS2 (0.56) | PTGS2LMNASMN1; SMN2HTTMAPT | |
| SCHEMBL14503143 | 0.91 | PTGS2 (0.56) | PTGS2LMNASMN1; SMN2HTTMAPT | |
| SCHEMBL14503139 | 0.90 | PTGS2 (0.47) | PTGS2LMNASMN1; SMN2HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |