Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.45 |
| ▸ | TCF7L2 | Q9NQB0 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14503191 | 0.94 | PTGS2 (0.57) | PTGS2MAPTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL14503163 | 0.94 | PTGS2 (0.57) | PTGS2MAPTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL14503676 | 0.88 | PTGS2 (0.52) | PTGS2MAPTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL5380874 | 0.88 | ALDH1A1 (0.46) | PTGS2MAPTALDH1A1CYP2C9HPGD | |
| SCHEMBL14503628 | 0.88 | MAPT (0.49) | PTGS2MAPTALDH1A1CYP2C9HPGD | |
| SCHEMBL14503642 | 0.87 | PTGS2 (0.53) | PTGS2MAPTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL14503664 | 0.86 | PTGS2 (0.49) | PTGS2MAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL14503398 | 0.86 | LMNA (0.58) | PTGS2MAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL14503227 | 0.85 | PTGS2 (0.56) | PTGS2MAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL14503143 | 0.85 | PTGS2 (0.56) | PTGS2MAPTALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |