Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | GBA1 | P04062 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5457162 | 0.82 | CA12 (0.40) | PTGS2NPSR1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL14503524 | 0.76 | PTGS2 (0.54) | PTGS2NPSR1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL14504129 | 0.74 | PTGS2 (0.61) | PTGS2NPSR1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL14503163 | 0.74 | PTGS2 (0.57) | PTGS2NPSR1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL14503191 | 0.74 | PTGS2 (0.57) | PTGS2NPSR1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL14503407 | 0.73 | MEN1 (0.52) | PTGS2NPSR1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL14503143 | 0.73 | PTGS2 (0.56) | PTGS2NPSR1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL14503227 | 0.73 | PTGS2 (0.56) | PTGS2NPSR1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL14503238 | 0.72 | BACE1 (0.55) | PTGS2NPSR1MAPTSMN1; SMN2NPC1 | |
| SCHEMBL14503609 | 0.72 | PTGS2 (0.55) | PTGS2NPSR1MAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |