Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | RORC | P51449 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14503398 | 0.92 | LMNA (0.58) | MEN1KMT2ALMNAALOX15TSHR | |
| SCHEMBL14503143 | 0.92 | PTGS2 (0.56) | MEN1KMT2ALMNAHSD17B10RORC | |
| SCHEMBL14503227 | 0.92 | PTGS2 (0.56) | MEN1KMT2ALMNAHSD17B10RORC | |
| SCHEMBL14503524 | 0.88 | PTGS2 (0.54) | MEN1KMT2ALMNAPTGS2SMN1; SMN2 | |
| SCHEMBL14503584 | 0.86 | ALDH1A1 (0.51) | MEN1KMT2ALMNAHSD17B10RORC | |
| SCHEMBL5400796 | 0.86 | SCN9A (0.42) | MEN1KMT2ALMNAALOX15TSHR | |
| SCHEMBL14503163 | 0.85 | PTGS2 (0.57) | MEN1KMT2ALMNAALOX15TSHR | |
| SCHEMBL14503191 | 0.85 | PTGS2 (0.57) | MEN1KMT2ALMNAALOX15TSHR | |
| SCHEMBL14503697 | 0.85 | CA12 (0.49) | MEN1KMT2ALMNAHSD17B10RORC | |
| SCHEMBL14503582 | 0.85 | PTGS2 (0.51) | MEN1KMT2ARORCPTGS2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |