Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | FASN | P49327 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5401247 | 0.84 | MAPK1 (0.54) | MAPK1ALDH1A1FASNMAPTCYP2C9 | |
| SCHEMBL14503148 | 0.80 | MAPT (0.55) | MAPK1ALDH1A1MAPTNPSR1KMT2A | |
| SCHEMBL14503062 | 0.80 | NPSR1 (0.56) | MAPK1ALDH1A1SMN1; SMN2MAPTCYP2C9 | |
| SCHEMBL14503557 | 0.78 | PTGS2 (0.50) | ALDH1A1SMN1; SMN2MAPTCYP2C9NPSR1 | |
| SCHEMBL14503065 | 0.77 | EDNRA (0.55) | CYP2C9KMT2A | |
| SCHEMBL14504503 | 0.76 | NPSR1 (0.68) | ALDH1A1SMN1; SMN2MAPTNPSR1KMT2A | |
| SCHEMBL14503056 | 0.75 | CA1 (0.76) | MAPTNPSR1KMT2APTGS2LMNA | |
| SCHEMBL14503488 | 0.74 | ESR1 (0.60) | ALDH1A1NPSR1KMT2APTGS2LMNA | |
| SCHEMBL14081433 | 0.73 | MAPT (0.78) | MAPK1ALDH1A1FASNMAPTCYP2C9 | |
| SCHEMBL14503936 | 0.73 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2MAPTCYP2C9NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |