Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | GBA1 | P04062 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GALR2 | O43603 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5382192 | 0.84 | LMNA (0.52) | MAPTLMNAGBA1MEN1KMT2A | |
| SCHEMBL14503530 | 0.80 | MAPK1 (0.58) | MAPTLMNAPTGS2KMT2ANPSR1 | |
| SCHEMBL14503015 | 0.79 | MEN1 (0.75) | MAPTLMNAGBA1PTGS2MEN1 | |
| SCHEMBL14503062 | 0.79 | NPSR1 (0.56) | MAPTLMNAPTGS2KMT2ANPSR1 | |
| SCHEMBL29028843 | 0.75 | MEN1 (0.77) | MAPTLMNAGBA1MEN1KMT2A | |
| SCHEMBL14504503 | 0.75 | NPSR1 (0.68) | MAPTLMNAGBA1PTGS2MEN1 | |
| SCHEMBL14503557 | 0.75 | PTGS2 (0.50) | MAPTLMNAPTGS2MEN1KMT2A | |
| SCHEMBL14503056 | 0.75 | CA1 (0.76) | MAPTLMNAPTGS2MEN1KMT2A | |
| SCHEMBL14503065 | 0.74 | EDNRA (0.55) | MEN1KMT2A | |
| SCHEMBL14503402 | 0.74 | ROCK2 (0.56) | MAPTLMNAMEN1KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |