Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.74 |
| ▸ | GAA | P10253 | 2/20 | 0.74 |
| ▸ | MAPT | P10636 | 8/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.69 |
| ▸ | HTT | P42858 | 5/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | BLM | P54132 | 2/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 5/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | CTSL | P07711 | 2/20 | 0.55 |
| ▸ | CTSS | P25774 | 2/20 | 0.55 |
| ▸ | CTSK | P43235 | 2/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14502988 | 0.94 | MEN1 (0.83) | MEN1KMT2AGAAMAPTALDH1A1 | |
| SCHEMBL5392856 | 0.83 | KMT2A (0.55) | MEN1KMT2AGAAMAPTALDH1A1 | |
| SCHEMBL18953047 | 0.81 | CTSL (0.79) | MEN1KMT2AGAAMAPTALDH1A1 | |
| SCHEMBL18953055 | 0.81 | CTSL (0.79) | MEN1KMT2AGAAMAPTALDH1A1 | |
| SCHEMBL14503056 | 0.81 | CA1 (0.76) | MEN1KMT2AGAAMAPTLMNA | |
| SCHEMBL14503655 | 0.79 | CTSL (0.64) | MEN1KMT2AGAAMAPTALDH1A1 | |
| SCHEMBL14504503 | 0.77 | NPSR1 (0.68) | MEN1KMT2AGAAMAPTALDH1A1 | |
| SCHEMBL14438981 | 0.77 | MEN1 (0.78) | MEN1KMT2AGAAMAPTALDH1A1 | |
| SCHEMBL14504236 | 0.75 | GAA (0.80) | MEN1KMT2AGAAMAPTALDH1A1 | |
| SCHEMBL14504499 | 0.75 | MEN1 (0.57) | MEN1KMT2AGAAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |