Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5395733 | 0.82 | MAPT (0.42) | MEN1KMT2AGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL14502988 | 0.80 | MEN1 (0.83) | MEN1KMT2AGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL14503655 | 0.78 | CTSL (0.64) | MEN1KMT2AGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL14503926 | 0.78 | PTGS2 (0.56) | MEN1KMT2AGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL14428348 | 0.78 | ABCG2 (0.51) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL14503691 | 0.76 | IDH2 (0.50) | MEN1KMT2AGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL14503535 | 0.75 | MEN1 (0.74) | MEN1KMT2AGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL14428347 | 0.73 | TDP1 (0.37) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL14504089 | 0.73 | CA12 (0.52) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL14503948 | 0.72 | KMT2A (0.52) | MEN1KMT2AGAAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |