Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.79 |
| ▸ | CTSS | P25774 | 3/20 | 0.79 |
| ▸ | CTSK | P43235 | 3/20 | 0.79 |
| ▸ | CTSB | P07858 | 2/20 | 0.79 |
| ▸ | MAPT | P10636 | 7/20 | 0.67 |
| ▸ | CA12 | O43570 | 2/20 | 0.65 |
| ▸ | CA1 | P00915 | 2/20 | 0.65 |
| ▸ | CA2 | P00918 | 2/20 | 0.65 |
| ▸ | CA9 | Q16790 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 7/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 5/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18953047 | 1.00 | CTSL (0.79) | CTSLCTSSCTSKCTSBMAPT | |
| SCHEMBL14502988 | 0.86 | MEN1 (0.83) | CTSLCTSSCTSKCTSBMAPT | |
| SCHEMBL14503535 | 0.81 | MEN1 (0.74) | CTSLCTSSCTSKCTSBMAPT | |
| SCHEMBL13942699 | 0.81 | KMT2A (0.77) | CTSLCTSSCTSKCTSBMAPT | |
| SCHEMBL31549907 | 0.80 | KMT2A (0.65) | CTSLCTSSCTSKCTSBMAPT | |
| SCHEMBL11810697 | 0.79 | LMNA (1.00) | MAPTCA12CA1CA2CA9 | |
| SCHEMBL32683 | 0.77 | PIK3CA (0.75) | — | |
| SCHEMBL5387635 | 0.77 | MEN1 (0.59) | CTSLCTSSCTSKCTSBMAPT | |
| SCHEMBL14503021 | 0.77 | LMNA (0.70) | MAPTCA12CA1CA2CA9 | |
| SCHEMBL11812589 | 0.76 | LMNA (0.94) | MAPTCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230272077-A1 | PD-1 SIGNAL INHIBITOR COMBINATION THERAPY | KYOTO UNIVERSITY (JP) | 2023-08-31 | — | — | US | disclosed |
| US-20230265193-A1 | PD-1 SIGNAL INHIBITOR COMBINATION THERAPY | KYOTO UNIVERSITY (JP) | 2023-08-24 | — | — | US | disclosed |
| EP-4218819-A2 | COMBINATION THERAPY BASED ON PD-1 SIGNAL INHIBITORS | Kyoto University (JP) | 2023-08-02 | — | — | EP | disclosed |
| US-20180362650-A1 | PD-1 SIGNAL INHIBITOR COMBINATION THERAPY | KYOTO UNIVERSITY (JP) | 2018-12-20 | — | — | US | disclosed |
| EP-3388084-A1 | PD-1 SIGNAL INHIBITOR COMBINATION THERAPY | Kyoto University (JP) | 2018-10-17 | — | — | EP | disclosed |
| WO-2017099034-A1 | PD-1 SIGNAL INHIBITOR COMBINATION THERAPY | 国立大学法人京都大学 | 2017-06-15 | — | — | WO | disclosed |