Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | GBA1 | P04062 | 2/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14505245 | 0.96 | MAPT (0.50) | MAPTGFERGAAKMT2APTGS2 | |
| SCHEMBL14504770 | 0.90 | PTGS2 (0.47) | MAPTGFERKMT2APTGS2LMNA | |
| SCHEMBL14503543 | 0.90 | MAPT (0.55) | MAPTGFERKMT2APTGS2LMNA | |
| SCHEMBL14505221 | 0.88 | PNLIP (0.49) | MAPTGFERGAAKMT2APTGS2 | |
| SCHEMBL14503231 | 0.86 | CA12 (0.50) | MAPTKMT2APTGS2LMNASMN1; SMN2 | |
| SCHEMBL5383965 | 0.85 | MAPT (0.43) | MAPTGFERGAAKMT2ANPSR1 | |
| SCHEMBL14505239 | 0.85 | MAPT (0.60) | MAPTGFERGAAKMT2APTGS2 | |
| SCHEMBL14503524 | 0.84 | PTGS2 (0.54) | MAPTGAAKMT2APTGS2LMNA | |
| SCHEMBL14504600 | 0.84 | PTGS2 (0.51) | MAPTGAAKMT2APTGS2LMNA | |
| SCHEMBL14504681 | 0.83 | MAPT (0.54) | MAPTKMT2APTGS2LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |