Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | GFER | P55789 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 4/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | CA9 | Q16790 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | AHR | P35869 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14505245 | 0.90 | MAPT (0.50) | MAPTGFERGAAPTGS2NPSR1 | |
| SCHEMBL14505221 | 0.87 | PNLIP (0.49) | MAPTGFERGAAPTGS2NPSR1 | |
| SCHEMBL14504906 | 0.86 | MAPT (0.56) | MAPTGFERGAAPTGS2NPSR1 | |
| SCHEMBL14503546 | 0.85 | MAPT (0.54) | MAPTGFERGAAPTGS2NPSR1 | |
| SCHEMBL5387678 | 0.85 | GAA (0.44) | MAPTGFERGAAPTGS2SMN1; SMN2 | |
| SCHEMBL5387702 | 0.85 | GAA (0.44) | MAPTGFERGAAPTGS2SMN1; SMN2 | |
| SCHEMBL14503834 | 0.80 | PTGS2 (0.56) | MAPTGAAPTGS2NPSR1CA12 | |
| SCHEMBL14504902 | 0.80 | NPSR1 (0.60) | MAPTGAAPTGS2NPSR1CA12 | |
| SCHEMBL14504774 | 0.80 | NPSR1 (0.54) | MAPTGAAPTGS2NPSR1CA12 | |
| SCHEMBL14505063 | 0.79 | PTGS2 (0.55) | MAPTGFERGAAPTGS2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |