Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14503585 | 0.92 | CA12 (0.46) | MAPTMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL14503676 | 0.89 | PTGS2 (0.52) | MAPTMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL5385112 | 0.88 | APP (0.38) | MAPTROCK1APPRAB9ACCNE1 | |
| SCHEMBL14503163 | 0.87 | PTGS2 (0.57) | MAPTMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL14503191 | 0.87 | PTGS2 (0.57) | MAPTMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL14503642 | 0.84 | PTGS2 (0.53) | MAPTMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL14503591 | 0.83 | CA12 (0.44) | MAPTMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL14503139 | 0.83 | PTGS2 (0.47) | MAPTMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL14503664 | 0.83 | PTGS2 (0.49) | MAPTMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL14503548 | 0.83 | PTGS2 (0.53) | MAPTMEN1KMT2ASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |