Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.63 |
| ▸ | GAA | P10253 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | HTT | P42858 | 3/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CRHBP | P24387 | 1/20 | 0.57 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.57 |
| ▸ | GBA1 | P04062 | 5/20 | 0.57 |
| ▸ | KDM1A | O60341 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14503314 | 0.85 | LMNA (0.58) | MAPTALOX15ALDH1A1HTTTSHR | |
| SCHEMBL14503358 | 0.84 | MAPT (0.65) | MAPTALOX15GAAHTTTSHR | |
| SCHEMBL27786579 | 0.82 | LMNA (0.60) | MAPTALOX15GAAALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL3641122 | 0.81 | LMNA (0.61) | MAPTALOX15GAAALDH1A1HTT | |
| SCHEMBL5401209 | 0.81 | GAA (0.47) | MAPTALOX15GAAALDH1A1HTT | |
| SCHEMBL14503262 | 0.78 | ACHE (0.65) | HTTNPSR1LMNAMEN1KMT2A | |
| SCHEMBL13947036 | 0.78 | PIK3CA (0.60) | MAPTALOX15GAAALDH1A1HTT | |
| SCHEMBL14503870 | 0.77 | NPSR1 (0.54) | MAPTGAAALDH1A1HTTTSHR | |
| SCHEMBL2460137 | 0.77 | L3MBTL1 (1.00) | MAPTALOX15GAAALDH1A1HTT | |
| SCHEMBL13944374 | 0.77 | PIK3CA (0.58) | MAPTALOX15GAAALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |