Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA9 | Q16790 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | IDH2 | P48735 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14504490 | 0.92 | CA12 (0.47) | NPSR1PTGS2HTTKMT2AMEN1 | |
| SCHEMBL14504774 | 0.89 | NPSR1 (0.54) | NPSR1PTGS2HTTKMT2AMEN1 | |
| SCHEMBL5396889 | 0.85 | ALOX15 (0.41) | HTTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL14503595 | 0.85 | RAB9A (0.54) | NPSR1PTGS2HTTKMT2AMEN1 | |
| SCHEMBL14503231 | 0.84 | CA12 (0.50) | NPSR1PTGS2HTTKMT2AMEN1 | |
| SCHEMBL14504207 | 0.84 | KMT2A (0.58) | NPSR1PTGS2HTTKMT2AMEN1 | |
| SCHEMBL14504974 | 0.83 | NPSR1 (0.51) | NPSR1PTGS2HTTKMT2AMEN1 | |
| SCHEMBL14503321 | 0.82 | SMN1; SMN2 (0.54) | NPSR1PTGS2HTTKMT2AMEN1 | |
| SCHEMBL14505245 | 0.81 | MAPT (0.50) | NPSR1PTGS2HTTKMT2AMEN1 | |
| SCHEMBL14503546 | 0.81 | MAPT (0.54) | NPSR1PTGS2HTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |