Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 3/20 | 0.52 |
| ▸ | FABP4 | P15090 | 3/20 | 0.52 |
| ▸ | RPA1 | P27694 | 2/20 | 0.51 |
| ▸ | KCNJ6 | P48051 | 2/20 | 0.50 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | CCKAR | P32238 | 5/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.47 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.46 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | MARS1 | P56192 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14504928 | 0.87 | PTGS2 (0.47) | FABP3FABP4RPA1KCNJ6KCNJ3 | |
| SCHEMBL14504449 | 0.84 | MGLL (0.52) | RPA1KCNJ6KCNJ3MGLLKCNJ5 | |
| SCHEMBL14504805 | 0.83 | PTGS2 (0.46) | FABP3FABP4RPA1KCNJ6KCNJ3 | |
| SCHEMBL5152488 | 0.83 | FABP3 (0.45) | FABP3FABP4RPA1KCNJ6KCNJ3 | |
| SCHEMBL14505146 | 0.83 | RPA1 (0.56) | FABP3FABP4RPA1CCKARRXRA | |
| SCHEMBL14504781 | 0.83 | PTGS2 (0.46) | FABP3FABP4RPA1KCNJ6KCNJ3 | |
| SCHEMBL14504441 | 0.81 | PTGS2 (0.46) | RPA1KCNJ6KCNJ3MGLLCCKAR | |
| SCHEMBL13352411 | 0.80 | CCKAR (0.48) | RPA1KCNJ6KCNJ3CCKARPTGS1 | |
| SCHEMBL14504573 | 0.80 | PTGS2 (0.46) | FABP3FABP4KCNJ6KCNJ3MALT1 | |
| SCHEMBL13157644 | 0.80 | PTGS2 (0.49) | FABP3FABP4RPA1MGLLBCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070112037-A1 | Pyrazole Derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2007-05-17 | — | — | US | disclosed |
| US-20070112037-A1 | Pyrazole Derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2007-05-17 | — | — | US | disclosed |
| US-7183306-B2 | Pyrazole derivatives | ASTELLAS PHARMA INC. (JP) | 2007-02-27 | — | — | US | disclosed |
| US-7183306-B2 | Pyrazole derivatives | ASTELLAS PHARMA INC. (JP) | 2007-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112037-A1 | Pyrazole Derivatives | CYP11B2, CYP11B1, CYP3A43 | FABP3 3873/4885FABP4 3914/4885RPA1 2143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.