Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDE1B | Q01064 | 4/20 | 0.35 |
| ▸ | PDE1A | P54750 | 3/20 | 0.35 |
| ▸ | PDE1C | Q14123 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PDE9A | O76083 | 2/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5424794 | 0.90 | MEN1 (0.36) | MEN1KMT2APDE1BPDE1APDE1C | |
| SCHEMBL5438108 | 0.89 | KMT2A (0.37) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL5430713 | 0.86 | PDE1C (0.37) | MEN1KMT2APDE1BPDE1APDE1C | |
| SCHEMBL5434685 | 0.85 | PPARD (0.34) | MEN1KMT2AALDH1A1LMNAHTT | |
| SCHEMBL5421018 | 0.85 | PKM (0.33) | MEN1KMT2AALDH1A1LMNAHTT | |
| SCHEMBL4967431 | 0.85 | KMT2A (0.40) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL5427742 | 0.85 | PKM (0.34) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL4965523 | 0.84 | ALDH1A1 (0.33) | ALDH1A1LMNAHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL5427803 | 0.84 | MEN1 (0.37) | MEN1KMT2APDE1BPDE1APDE1C | |
| SCHEMBL5431866 | 0.84 | PDE1A (0.39) | MEN1KMT2APDE1BPDE1APDE1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070099915-A1 | INHIBITORS OF THE HIV INTEGRASE ENZYME | PFIZER INC. | 2007-05-03 | — | — | US | disclosed |
| US-20070099915-A1 | INHIBITORS OF THE HIV INTEGRASE ENZYME | PFIZER INC. | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099915-A1 | INHIBITORS OF THE HIV INTEGRASE ENZYME | IMPDH1, INTS9, TYMP | MEN1 4787/4885KMT2A 1367/4885PDE1B 3306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.