Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 7/20 | 0.48 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.46 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.46 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | PTPRC | P08575 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | LPL | P06858 | 1/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL172731 | 0.82 | ERN1 (0.57) | KCNH2CYP2A6CYP2E1CYP2B6ACMSD | |
| SCHEMBL3468319 | 0.82 | KCNH2 (0.69) | KCNH2CYP2A6CYP2E1CYP2B6ACMSD | |
| SCHEMBL18717328 | 0.82 | KCNH2 (0.69) | KCNH2CYP2A6CYP2E1CYP2B6ACMSD | |
| SCHEMBL27971830 | 0.82 | KCNH2 (0.48) | KCNH2CYP2A6CYP2E1CYP2B6ACMSD | |
| SCHEMBL5992568 | 0.79 | GAK (0.48) | KCNH2CYP2A6ERN1PDGFRBPDGFRA | |
| SCHEMBL26414634 | 0.79 | ERN1 (0.50) | KCNH2CYP2A6ERN1PDGFRBPDGFRA | |
| SCHEMBL19354608 | 0.79 | KCNH2 (0.46) | KCNH2CYP2A6CYP2E1CYP2B6ACMSD | |
| SCHEMBL19317255 | 0.79 | KCNH2 (0.46) | KCNH2CYP2A6CYP2E1CYP2B6ACMSD | |
| SCHEMBL29702110 | 0.78 | ALDH1A1 (0.55) | MCL1 | |
| SCHEMBL3084322 | 0.78 | ALDH1A1 (0.55) | MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017155910-A1 | THIAZOLIDINONE COMPOUNDS AND USE THEREOF | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2017-09-14 | — | — | WO | disclosed |
| US-20170253569-A1 | THIAZOLIDINONE COMPOUNDS AND USE THEREOF | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2017-09-07 | — | — | US | disclosed |
| US-20070116984-A1 | SPIRO-COMPOUND FOR ELECTROLUMINESCENT DISPLAY DEVICE AND ELECTROLUMINESCENT DISPLAY DEVICE COMPRISING THE SAME | DOOSAN CORPORATION (KR) | 2007-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170253569-A1 | THIAZOLIDINONE COMPOUNDS AND USE THEREOF | OPRL1, OPRD1, OPRK1 | KCNH2 2159/4885CYP2A6 80/4885CYP2E1 162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.