Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.41 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | BRD2 | P25440 | 1/20 | 0.40 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.40 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.40 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | FABP6 | P51161 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27774707 | 0.90 | TLR8 (0.52) | TLR8NPC1BRD4KDM4EALDH1A1 | |
| SCHEMBL23805183 | 0.86 | KDM4E (0.42) | TLR8NPC1MAP2K2MAP2K1BRD4 | |
| SCHEMBL3161296 | 0.84 | L3MBTL1 (0.45) | BRD4KDM4EALDH1A1BRD2BRD3 | |
| SCHEMBL14507440 | 0.83 | EPHX2 (0.56) | TLR8MAP2K2MAP2K1BRD4KDM4E | |
| SCHEMBL6496861 | 0.81 | TLR8 (0.41) | TLR8MAP2K2MAP2K1BRD4KDM4E | |
| SCHEMBL21395223 | 0.80 | LMNA (0.59) | TLR8BRD4KDM4EALDH1A1BRD2 | |
| SCHEMBL14507698 | 0.80 | ALDH1A1 (0.36) | TLR8NPC1BRD4KDM4EALDH1A1 | |
| SCHEMBL12095050 | 0.79 | KDM4E (0.43) | TLR8BRD4KDM4EALDH1A1BRD2 | |
| SCHEMBL13701807 | 0.76 | BRD4 (0.45) | BRD4ALDH1A1BRD2BRD3BRDT | |
| SCHEMBL13039896 | 0.76 | LMNA (0.43) | BRD4KDM4EALDH1A1BRD2BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007067836-A2 | SUBSTITUTED PYRAZOLE COMPOUNDS USEFUL AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-06-14 | — | — | WO | disclosed |