Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14275841 | 0.78 | MAPT (0.36) | MAPTGAAALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL12381790 | 0.78 | MAPT (0.36) | MAPTGAAALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL11912104 | 0.76 | MAPT (0.41) | L3MBTL1MAPTGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL13802677 | 0.76 | MAPT (0.41) | L3MBTL1MAPTGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL20196370 | 0.73 | MAPT (0.33) | L3MBTL1MAPTGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL6956406 | 0.73 | — | — | |
| SCHEMBL1698550 | 0.73 | SMN1; SMN2 (0.41) | L3MBTL1MAPTGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL3751829 | 0.71 | MAPT (0.57) | L3MBTL1MAPTSMN1; SMN2KMT2ACHRM2 | |
| SCHEMBL19262494 | 0.71 | MAPT (0.57) | L3MBTL1MAPTSMN1; SMN2KMT2ACHRM2 | |
| SCHEMBL1705495 | 0.70 | CRBN (0.43) | L3MBTL1CRBNMAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200172527-A1 | BENZOXAZINONE DERIVATIVES USEFUL AS HERBICIDES | REDAG CROP PROT LTD (GB) | 2020-06-04 | — | — | US | disclosed |
| US-20140179686-A1 | Novel Vanilloid Receptor Ligands and Use Thereof for the Production of Pharmaceutical Preparations | GRUENENTHAL GMBH (DE) | 2014-06-26 | — | — | US | disclosed |
| US-8710233-B2 | Vanilloid receptor ligands and use thereof for the production of pharmaceutical preparations | GRUENENTHAL GMBH (DE) | 2014-04-29 | — | — | US | disclosed |
| US-20070105861-A1 | NOVEL VANILLOID RECEPTOR LIGANDS AND USE THEREOF FOR THE PRODUCTION OF PHARMACEUTICAL PREPARATIONS | GRUENENTHAL GMBH (DE) | 2007-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105861-A1 | NOVEL VANILLOID RECEPTOR LIGANDS AND USE THEREOF FOR THE PRODUCTION OF PHARMACEUTICAL PREPARATIONS | TRPV1, TRPV5, TRPV2 | L3MBTL1 4845/4885CRBN 3141/4885MAPT 4129/4885 |
| US-20200172527-A1 | BENZOXAZINONE DERIVATIVES USEFUL AS HERBICIDES | CBR3, CBR1, CYP4X1 | L3MBTL1 3558/4885CRBN 2720/4885MAPT 4014/4885 |
| US-20140179686-A1 | Novel Vanilloid Receptor Ligands and Use Thereof for the Production of Pharmaceutical Preparations | TRPV1, TRPV5, TRPV2 | L3MBTL1 4845/4885CRBN 3141/4885MAPT 4129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.