SCHEMBL1450852

SCHEMBL1450852

FC(F)(F)c1cc(C(F)(F)F)cc([Al-](c2cc(C(F)(F)F)cc(C(F)(F)F)c2)(c2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.44
IDO1 P14902 2/20 0.39
ADRB1 P08588 1/20 0.35
GAA P10253 1/20 0.35
TSHR P16473 3/20 0.35
ALDH1A1 P00352 2/20 0.35
MAPT P10636 2/20 0.34
RAPGEF4 Q8WZA2 1/20 0.34
ITGB3 P05106 1/20 0.34
ITGAV P06756 1/20 0.34
RXRA P19793 1/20 0.34
RXRB P28702 1/20 0.34
RXRG P48443 1/20 0.34
XPO1 O14980 1/20 0.32
CA2 P00918 1/20 0.32
CYP3A4 P08684 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
HIF1A Q16665 1/20 0.32
TXNRD1 Q16881 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1451900 0.97 CES2 (0.42) CES2IDO1ADRB1GAATSHR
SCHEMBL913365 0.97 CES2 (0.42) CES2IDO1ADRB1GAATSHR
Lithium Ion SCHEMBL1451316 0.97 CES2 (0.42) CES2IDO1ADRB1GAATSHR
Potassium Ion SCHEMBL1451670 0.97 CES2 (0.42) CES2IDO1ADRB1GAATSHR
SCHEMBL6142806 0.97 CES2 (0.42) CES2IDO1ADRB1GAATSHR
SCHEMBL440959 0.80 CES2 (0.58) CES2IDO1ADRB1TSHRALDH1A1
SCHEMBL4258831 0.79 ALDH1A1 (0.41) IDO1TSHRALDH1A1MAPTKDM4E
SCHEMBL4264056 0.77 CTSL (0.38) GAAALDH1A1MAPTRAPGEF4RXRA
SCHEMBL12816202 0.77 ALDH1A1 (0.39) IDO1TSHRALDH1A1MAPT
SCHEMBL2095504 0.75 CES2 (0.48) CES2IDO1ADRB1GAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3344671-B1 POLYCYCLOOLEFIN POLYMER COMPOSITIONS AS OPTICAL MATERIALS PROMERUS LLC (US) 2019-11-06 EP claimed
EP-1680218-A2 SINGLE COMPONENT CATIONIC PALLADIUM PROINITIATORS FOR THE LATENT POLYMERIZATION OF CYCLOOLEFINS Promerus, LLC (US) 2006-07-19 EP claimed
US-6936672-B2 Mold addition polymerization of norbornene-type monomers using group 10 metal complexes SUMITOMO BAKELITE CO., LTD. (JP) 2005-08-30 US claimed
US-20050187398-A1 Single component cationic palladium proinitiators for the latent polymerization of cycloolefins PROMERUS, LLC 2005-08-25 US claimed
EP-1155057-B1 IN MOLD ADDITION POLYMERIZATION OF NORBORNENE-TYPE MONOMERS USING GROUP 10 METAL COMPLEXES SUMITOMO BAKELITE CO (JP) 2005-06-22 EP claimed
WO-2005042147-A2 SINGLE COMPONENT CATIONIC PALLADIUM PROINITIATORS FOR THE LATENT POLYMERIZATION OF CYCLOOLEFINS PROMERUS, LLC (US) 2005-05-12 WO claimed
EP-1034196-B1 CATALYST AND METHODS FOR POLYMERIZING CYCLOOLEFINS PROMERUS LLC (US) 2005-01-12 EP claimed
US-20030120006-A1 In mold addition polymerization of norbornene-type monomers using group 10 metal complexes THE B.F. GOODRICH COMPANY 2003-06-26 US claimed
US-20030023013-A1 Catalyst and methods for polymerizing cycloolefins THE B.F.GOODRICH COMPANY 2003-01-30 US claimed
US-6455650-B1 CONTACTING POLYCYCLOOLEFIN MONOMER WITH A HIGH ACTIVITY GROUP 10 TRANSITION METAL CATALYST COMPLEX TO OBTAIN POLYMER PRODUCT THE B.F. GOODRICH COMPANY 2002-09-24 US claimed
US-20020052454-A1 CATALYST AND METHODS FOR POLYMERIZING CYCLOOLEFINS SUMITOMO BAKELITE CO., LTD. (JP) 2002-05-02 US claimed
US-6350832-B1 CATALYTIC COSSLINKING POLYMER OF POLYCYCLOOLEFIN MONOMER, MOLDING AND SHAPING IN THE PRESENCE OF GROUP 10 TRANSITION METAL AND ANION THE B. F. GOODRICH COMPANY 2002-02-26 US claimed
EP-1155057-A1 IN MOLD ADDITION POLYMERIZATION OF NORBORNENE-TYPE MONOMERS USING GROUP 10 METAL COMPLEXES The B.F.Goodrich Co. (US) 2001-11-21 EP claimed
EP-1034196-A1 CATALYST AND METHODS FOR POLYMERIZING CYCLOOLEFINS THE B.F. GOODRICH COMPANY (US) 2000-09-13 EP claimed
WO-2000034344-A1 IN MOLD ADDITION POLYMERIZATION OF NORBORNENE-TYPE MONOMERS USING GROUP 10 METAL COMPLEXES THE B.F.GOODRICH COMPANY (US) 2000-06-15 WO claimed
WO-2000020472-A1 CATALYST AND METHODS FOR POLYMERIZING CYCLOOLEFINS THE B.F. GOODRICH COMPANY (US) 2000-04-13 WO claimed
WO-2024095078-A1 COMPOSITIONS INCLUDING A MIXTURE OF ISOMERS OF ITACONIMIDE NORBORNENE AND CITRACONIMIDE NORBORNENE 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-05-10 WO disclosed
WO-2023196366-A1 PALLADIUM CATALYSTS FOR FORMING VINYL ADDITION POLYMERS HAVING IMPROVED FILM FORMING PROPERTIES PROMERUS, LLC (US) 2023-10-12 WO disclosed
US-5474962-A Powder catalyst composition and process for polymerizing olefins with the use thereof MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) 1995-12-12 US disclosed
EP-0589638-A2 Powder catalyst composition and process for polymerizing olefins with the use thereof MITSUBISHI CHEMICAL CORPORATION (JP) 1994-03-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050187398-A1 Single component cationic palladium proinitiators for the latent polymerization of cycloolefins LRRK2, LBR, SNCA CES2 3409/4885IDO1 698/4885ADRB1 514/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.