Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.43 |
| ▸ | HTR2A | P28223 | 6/20 | 0.43 |
| ▸ | HTR2B | P41595 | 4/20 | 0.43 |
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | HRH1 | P35367 | 4/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13880282 | 0.80 | PDE7A (0.39) | HTR2AHTR2BHTR2CHRH1KMT2A | |
| SCHEMBL14508929 | 0.75 | TNKS (0.49) | SIGMAR1HTR2AHTR2BHTR2CDRD2 | |
| SCHEMBL8073186 | 0.74 | TNKS (0.45) | SIGMAR1HTR2AHTR2BHTR2C | |
| SCHEMBL30089988 | 0.74 | DRD4 (0.46) | SIGMAR1DRD2CHRM3 | |
| SCHEMBL7675241 | 0.74 | DRD4 (0.46) | SIGMAR1DRD2CHRM3 | |
| SCHEMBL23508644 | 0.73 | SIGMAR1 (0.49) | SIGMAR1HTR2AHTR2BHTR2C | |
| SCHEMBL3287322 | 0.73 | HRH3 (0.54) | SIGMAR1HTR2AHTR2BHTR2CCHRM2 | |
| SCHEMBL7821093 | 0.73 | KCNH2 (0.41) | SIGMAR1HTR2AHTR2BHTR2CDRD2 | |
| Hydrochloric Acid SCHEMBL7673355 | 0.72 | DRD4 (0.44) | SIGMAR1DRD2CHRM3 | |
| SCHEMBL14193181 | 0.72 | SIGMAR1 (0.49) | SIGMAR1HTR2AHTR2BHTR2CHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1795527-A1 | CARBAMOYL-SUBSTITUTED SPIRO DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-06-13 | — | — | EP | disclosed |