Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 14/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
| ▸ | EBP | Q15125 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8472418 | 0.91 | SIGMAR1 (0.45) | SIGMAR1HTR2AHTR2CHTR2BEBP | |
| SCHEMBL3767118 | 0.89 | HTR2A (0.54) | SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL14193181 | 0.83 | SIGMAR1 (0.49) | SIGMAR1HTR2AHTR2CHTR2BEBP | |
| SCHEMBL2743258 | 0.82 | SIGMAR1 (0.67) | SIGMAR1HTR2AHTR2CHTR2BEBP | |
| SCHEMBL12065337 | 0.79 | MAOA (0.46) | SIGMAR1HTR2AHTR2CHTR2BEBP | |
| SCHEMBL240450 | 0.79 | SIGMAR1 (0.68) | SIGMAR1HTR2AHTR2CHTR2BEBP | |
| SCHEMBL11937070 | 0.78 | SIGMAR1 (0.57) | SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL17969883 | 0.77 | KCNH2 (0.43) | SIGMAR1HTR2AHTR2CHTR2BEBP | |
| SCHEMBL3287322 | 0.77 | HRH3 (0.54) | SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL24284519 | 0.76 | SIGMAR1 (0.40) | SIGMAR1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021115286-A1 | SIX-MEMBERED AND FIVE-MEMBERED AROMATIC RING DERIVATIVE CONTAINING NITROGEN HETEROATOMS WHICH CAN BE USED AS SHP2 INHIBITOR | 成都倍特药业股份有限公司 | 2021-06-17 | — | — | WO | disclosed |