Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 3/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | DRD5 | P21918 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30089988 | 1.00 | DRD4 (0.46) | DRD4OPRM1SETD7CYP1A2CHRNA7 | |
| Hydrochloric Acid SCHEMBL7673355 | 0.98 | DRD4 (0.44) | DRD4OPRM1SETD7CYP1A2CHRNA7 | |
| SCHEMBL7674579 | 0.87 | DRD2 (0.47) | DRD4OPRM1CYP1A2CHRM3DRD2 | |
| SCHEMBL14508929 | 0.86 | TNKS (0.49) | DRD4OPRM1SETD7CYP1A2CHRNA7 | |
| SCHEMBL11258495 | 0.85 | SETD7 (0.47) | DRD4OPRM1SETD7SIGMAR1DRD2 | |
| SCHEMBL11392471 | 0.85 | DRD4 (0.41) | DRD4OPRM1SETD7CYP1A2CHRNA7 | |
| Bromide SCHEMBL11253158 | 0.83 | SETD7 (0.46) | DRD4OPRM1SETD7SIGMAR1DRD2 | |
| SCHEMBL11387860 | 0.83 | OPRD1 (0.51) | OPRM1CYP1A2SIGMAR1DRD2DRD1 | |
| Hydrochloric Acid SCHEMBL11440752 | 0.82 | OPRD1 (0.50) | OPRM1CYP1A2SIGMAR1DRD2DRD1 | |
| SCHEMBL11397125 | 0.81 | OPRM1 (0.46) | OPRM1DRD2DRD1DRD5DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6387893-B1 | ADRENERGIC BLOCKING AGENT; BENIGN PROSATATIC HYPERPLASIA | MERCK & CO., INC. | 2002-05-14 | — | — | US | disclosed |
| US-4268514-A | ANALGESICS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-05-19 | — | — | US | disclosed |