Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | BCR | P11274 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4646583 | 0.85 | TDP1 (0.75) | TDP1CYP3A4CA2PTPN1ALDH1A1 | |
| SCHEMBL1119927 | 0.83 | CA2 (0.56) | TPMTCYP3A4CA2CA4ALDH1A1 | |
| SCHEMBL9695064 | 0.82 | TPMT (0.58) | TPMTTDP1CYP3A4CA2CA4 | |
| SCHEMBL28008796 | 0.79 | CYP3A4 (0.56) | TDP1CYP3A4CA2CA4ALDH1A1 | |
| SCHEMBL4931686 | 0.78 | TPMT (0.55) | TPMTTDP1CYP3A4CA2CA4 | |
| SCHEMBL1402215 | 0.77 | CYP3A4 (0.60) | TPMTTDP1CYP3A4PTPN1MAPT | |
| SCHEMBL10106591 | 0.77 | PTPN1 (0.62) | TDP1CYP3A4PTPN1ALDH1A1MAPT | |
| SCHEMBL29421877 | 0.77 | PTPN1 (0.62) | TDP1CYP3A4PTPN1ALDH1A1MAPT | |
| SCHEMBL21614372 | 0.76 | CYP3A4 (0.52) | TDP1CYP3A4CA2ALDH1A1MAPT | |
| SCHEMBL1119249 | 0.75 | ALOX5 (0.54) | TDP1CYP3A4CA2CA4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220783-B2 | Para-terphenyl compounds | SHIONOGI & CO., LTD. (JP) | 2007-05-22 | — | — | US | disclosed |
| US-7220783-B2 | Para-terphenyl compounds | SHIONOGI & CO., LTD. (JP) | 2007-05-22 | — | — | US | disclosed |