Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 7/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9418420 | 0.88 | TDP1 (0.64) | TPMTHSD17B10ALOX15ALOX12TDP1 | |
| SCHEMBL14385352 | 0.85 | ALOX15 (0.62) | TPMTHSD17B10ALOX15ALOX12TDP1 | |
| SCHEMBL301662 | 0.83 | HSD17B10 (0.59) | TPMTHSD17B10ALOX15ALOX12TDP1 | |
| SCHEMBL14511772 | 0.82 | TPMT (0.58) | TPMTHSD17B10ALOX15ALOX12TDP1 | |
| SCHEMBL129971 | 0.80 | ALOX15 (0.56) | TPMTALOX15ALOX12TDP1TSHR | |
| SCHEMBL30927163 | 0.80 | ALOX15 (0.56) | TPMTALOX15ALOX12TDP1TSHR | |
| SCHEMBL16904136 | 0.80 | TDP1 (0.48) | TPMTHSD17B10ALOX15ALOX12TDP1 | |
| SCHEMBL21823580 | 0.78 | TPMT (0.55) | TPMTHSD17B10ALOX15ALOX12TDP1 | |
| SCHEMBL16596078 | 0.78 | TDP1 (0.46) | TPMTHSD17B10ALOX15ALOX12TDP1 | |
| SCHEMBL4931686 | 0.78 | TPMT (0.55) | TPMTHSD17B10ALOX15ALOX12TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471941-A2 | An improved process for the preparation of 5-bromo-2-methoxyresorcinol | AMERICAN CYANAMID COMPANY (US) | 1992-02-26 | — | — | EP | claimed |
| EP-0471941-A2 | An improved process for the preparation of 5-bromo-2-methoxyresorcinol | AMERICAN CYANAMID COMPANY (US) | 1992-02-26 | — | — | EP | disclosed |
| US-4379161-A | Novel substituted heterocyclic phenoxyamines, the method of preparation thereof and the use thereof as local anaesthetics | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE DE FRANCE (FR) | 1983-04-05 | — | — | US | disclosed |