Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | FHIT | P49789 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1720717 | 0.74 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL4175069 | 0.74 | KDM4E (0.33) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL22271633 | 0.70 | FHIT (0.35) | ALDH1A1MAPTHPGDHSD17B10FHIT | |
| SCHEMBL28428029 | 0.70 | FHIT (0.35) | ALDH1A1MAPTKDM4EHPGDFHIT | |
| SCHEMBL12709131 | 0.69 | ALDH1A1 (0.39) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL953974 | 0.69 | MAPT (0.32) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL17452191 | 0.68 | CYP1A2 (0.34) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL2890316 | 0.65 | — | — | |
| SCHEMBL21605471 | 0.64 | L3MBTL1 (0.57) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL20936366 | 0.63 | FHIT (0.34) | ALDH1A1KDM4EFHIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7214805-B2 | Process for the industrial synthesis of strontium ranelate and its hydrates | LES LABORATOIRES SERVIER (FR) | 2007-05-08 | — | — | US | disclosed |