Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | STAT1 | P42224 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14514766 | 0.86 | MAPT (0.34) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL14514733 | 0.84 | PTGS2 (0.40) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL14516759 | 0.82 | MAPT (0.49) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL14515976 | 0.81 | POLB (0.44) | MAPTNPC1RAB9AALDH1A1TDP1 | |
| SCHEMBL14514762 | 0.79 | CYP3A4 (0.33) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL14516137 | 0.79 | SMN1; SMN2 (0.49) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL14514851 | 0.76 | ACHE (0.37) | MAPTALDH1A1SMN1; SMN2MAPK1TDP1 | |
| SCHEMBL14514845 | 0.75 | KMT2A (0.46) | MAPTNPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL14516266 | 0.74 | MAPT (0.30) | MAPT | |
| SCHEMBL14514731 | 0.71 | ALDH1A1 (0.35) | MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7232467-B2 | Dyeing hair with capped diazonium compound; intense, striking coloration; light, shampoo and rub fastness; storage stability; nondamaging, nonstaining | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-06-19 | — | — | US | disclosed |
| US-7229479-B2 | Method of coloring porous material | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2007-06-12 | — | — | US | disclosed |