Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | STS | P08842 | 10/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | HPGD | P15428 | 7/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14514724 | 0.97 | ALDH1A1 (0.50) | MEN1KMT2ACA12CA1CA9 | |
| SCHEMBL4712308 | 0.89 | MEN1 (0.63) | MEN1KMT2ACA12CA1CA9 | |
| SCHEMBL9904020 | 0.84 | PRKD1 (0.58) | MEN1KMT2ACA12CA1CA9 | |
| SCHEMBL9904117 | 0.81 | LMNA (0.59) | MEN1KMT2ACA12CA1CA9 | |
| SCHEMBL14514719 | 0.78 | ALDH1A1 (0.57) | MEN1KMT2ASTSKDM4EALDH1A1 | |
| SCHEMBL14514722 | 0.77 | ALDH1A1 (0.53) | MEN1KMT2ASTSKDM4EALDH1A1 | |
| SCHEMBL4709135 | 0.76 | MEN1 (0.48) | MEN1KMT2ACA12CA1CA9 | |
| SCHEMBL4709560 | 0.75 | MEN1 (0.47) | MEN1KMT2ACA12CA1CA9 | |
| SCHEMBL29853363 | 0.74 | MAPT (0.63) | MEN1KMT2ACA12CA1CA9 | |
| SCHEMBL26781086 | 0.74 | MAPT (0.63) | MEN1KMT2ACA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217734-B2 | Substituted benzopyrans as selective estrogen receptor-beta agonists | ELI LILLY AND COMPANY (US) | 2007-05-15 | — | — | US | disclosed |