SCHEMBL14516004

SCHEMBL14516004

Cc1cc(C)cc(N(c2cc(C)cc(C)c2)c2ccc3c(-c4cccc5ccccc45)c4cc(N(c5cc(C)cc(C)c5)c5cc(C)cc(C)c5)ccc4c(-c4cccc5ccccc45)c3c2)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHFR P00374 1/20 0.38
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
CYP2A6 P11509 2/20 0.34
CYP1A2 P05177 1/20 0.34
KDM4E B2RXH2 3/20 0.34
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
SIGMAR1 Q99720 1/20 0.33
SOS1 Q07889 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CHRNA1 P02708 1/20 0.32
CHRNG P07510 1/20 0.32
CHRNB1 P11230 1/20 0.32
CHRNB2 P17787 1/20 0.32
SLC6A2 P23975 1/20 0.32
CHRNB4 P30926 1/20 0.32
SLC6A4 P31645 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA4 P43681 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14516009 0.96 DHFR (0.36) DHFRMAOAMAOBCYP2A6CYP1A2
SCHEMBL13345133 0.90 SOS1 (0.36) DHFRMAOAMAOBCYP2A6CYP1A2
SCHEMBL14099720 0.90 DHFR (0.39) DHFRMAOAMAOBCYP2A6CYP1A2
SCHEMBL13303900 0.89 SIGMAR1 (0.40) DHFRMAOAMAOBCYP1A2KDM4E
SCHEMBL15762789 0.87 DHFR (0.38) DHFRMAOAMAOBCYP1A2KDM4E
SCHEMBL15762770 0.87 DHFR (0.38) DHFRMAOAMAOBCYP1A2KDM4E
SCHEMBL13303915 0.87 SOS1 (0.36) DHFRCYP2A6CYP1A2KDM4ESOS1
SCHEMBL13333588 0.87 HTT (0.35) DHFRMAOAMAOBCYP2A6CYP1A2
SCHEMBL14516012 0.87 DHFR (0.34) DHFRKDM4ENPC1ALDH1A1HTR2A
SCHEMBL14516013 0.86 NCF1 (0.37) DHFRMAOACYP1A2KDM4ESOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8647753-B2 Organic electroluminescence device LG DISPLAY CO., LTD. (KR) 2014-02-11 US disclosed
US-8647753-B2 Organic electroluminescence device LG DISPLAY CO., LTD. (KR) 2014-02-11 US disclosed
US-20070087222-A1 Organic electroluminescence device LG DISPLAY CO., LTD. (KR) 2007-04-19 US disclosed
US-20070087222-A1 Organic electroluminescence device LG DISPLAY CO., LTD. (KR) 2007-04-19 US disclosed