Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAPDH | P04406 | 1/20 | 0.38 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.38 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4712217 | 0.92 | GAPDH (0.44) | GAPDHHSPA1AHSPA8MEN1CYP1A2 | |
| SCHEMBL4713073 | 0.83 | GAPDH (0.47) | GAPDHHSPA1AHSPA8MEN1CYP1A2 | |
| SCHEMBL4712017 | 0.81 | GAPDH (0.44) | GAPDHHSPA1AHSPA8MEN1CYP1A2 | |
| SCHEMBL4711434 | 0.80 | GAPDH (0.43) | GAPDHHSPA1AHSPA8MEN1CYP1A2 | |
| SCHEMBL4713160 | 0.79 | GAPDH (0.44) | GAPDHHSPA1AHSPA8MEN1CYP1A2 | |
| SCHEMBL4715026 | 0.79 | GAPDH (0.44) | GAPDHHSPA1AHSPA8MEN1CYP1A2 | |
| SCHEMBL4712093 | 0.79 | GAPDH (0.44) | GAPDHHSPA1AHSPA8MEN1CYP1A2 | |
| SCHEMBL4712064 | 0.79 | GAPDH (0.42) | GAPDHHSPA1AHSPA8MEN1CYP1A2 | |
| Potassium Ion SCHEMBL5355686 | 0.76 | GAPDH (0.35) | GAPDHHSPA1AHSPA8 | |
| SCHEMBL14143545 | 0.76 | CDC25B (0.35) | GAPDHHSPA1AHSPA8MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7199130-B2 | Substituted 5,6,6a, 11b-tetrahydro-7-oxa-5-aza-benzo[c]fluorene-6-carboxylic acid compounds as NMDA-antagonists | GRUENENTHAL GMBH (DE) | 2007-04-03 | — | — | US | disclosed |