Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | HSPA1A | P0DMV8 | 3/20 | 0.32 |
| ▸ | PTPN7 | P35236 | 3/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | HSPA8 | P11142 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | GAPDH | P04406 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14143776 | 0.87 | HSPA1A (0.35) | HSPA1APTPN7TDP1HSPA8KDM4E | |
| SCHEMBL14143750 | 0.84 | KDM4E (0.39) | HSPA1APTPN7TDP1HSPA8KDM4E | |
| SCHEMBL4712217 | 0.82 | GAPDH (0.44) | CDC25BHSPA1APTPN7TDP1HSPA8 | |
| SCHEMBL14143589 | 0.75 | GAPDH (0.32) | HSPA1APTPN7GAPDH | |
| SCHEMBL4713073 | 0.72 | GAPDH (0.47) | CDC25BHSPA1APTPN7TDP1HSPA8 | |
| SCHEMBL4712017 | 0.69 | GAPDH (0.44) | HSPA1APTPN7TDP1HSPA8MEN1 | |
| SCHEMBL4715026 | 0.69 | GAPDH (0.44) | HSPA1APTPN7TDP1HSPA8MEN1 | |
| SCHEMBL4713160 | 0.69 | GAPDH (0.44) | HSPA1APTPN7HSPA8MEN1GAPDH | |
| SCHEMBL4711434 | 0.67 | GAPDH (0.43) | HSPA1AHSPA8MEN1GAPDHKMT2A | |
| SCHEMBL4712064 | 0.67 | GAPDH (0.42) | HSPA1APTPN7TDP1HSPA8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412361-B1 | SUBSTITUTED 5,6,6A,11B-TETRAHYDRO-7-OXA-5-AZA-BENZO[C]FLUORENE-6-CARBOXYLIC ACID DERIVATIVES SERVING AS NMDA ANTAGONISTS | GRUENENTHAL GMBH (DE) | 2008-07-23 | — | — | EP | disclosed |