Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.38 |
| ▸ | NT5E | P21589 | 2/20 | 0.38 |
| ▸ | PNP | P00491 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CD99 | P14209 | 1/20 | 0.38 |
| ▸ | CHKA | P35790 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14518672 | 0.84 | ADORA3 (0.66) | ADORA3ADORA2AADORA1HSP90B1CHKA | |
| SCHEMBL5369682 | 0.83 | ADORA3 (0.48) | ADORA3ADORA2AADORA1PDE4DPDE3A | |
| SCHEMBL5372681 | 0.83 | ADORA3 (0.48) | ADORA3ADORA2AADORA1PDE4DPDE3A | |
| SCHEMBL14518669 | 0.83 | ADORA3 (0.55) | ADORA3ADORA2AADORA1HSP90B1NT5E | |
| SCHEMBL5363882 | 0.83 | ADORA3 (0.54) | ADORA3ADORA2AADORA1HSP90B1NT5E | |
| SCHEMBL14518670 | 0.75 | NT5E (0.45) | ADORA3ADORA2AADORA1PDE2ANT5E | |
| SCHEMBL14543434 | 0.75 | ADORA3 (0.58) | ADORA3ADORA2AADORA1HSP90B1NT5E | |
| SCHEMBL5359757 | 0.74 | ADORA3 (0.52) | ADORA3ADORA2AADORA1 | |
| SCHEMBL5359756 | 0.74 | ADORA3 (0.52) | ADORA3ADORA2AADORA1 | |
| SCHEMBL14543433 | 0.74 | ADORA3 (0.43) | ADORA3ADORA2AADORA1PDE4DPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7199127-B2 | Purine nucleosides | UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2007-04-03 | — | — | US | disclosed |
| US-20050256143-A1 | Purin-9-yl-tetrahydrothiophene-3,4-diols; anticarcinogenic agents selective to A3 adenosine receptors; breast cancer | Government of the United States of America, repres ented by The Secretary, Department of Health and (US) | 2005-11-17 | — | — | US | disclosed |
| EP-1578758-A2 | PURINE NUCLEOSIDES | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2005-09-28 | — | — | EP | disclosed |
| WO-2004038006-A2 | PURINE NUCLEOSIDES | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2004-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256143-A1 | Purin-9-yl-tetrahydrothiophene-3,4-diols; anticarcinogenic agents selective to A3 adenosine receptors; breast cancer | ADORA3, P2RX3, P2RY1 | ADORA3 1/4885ADORA2A 6/4885ADORA1 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.