Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2420027 | 0.81 | — | — | |
| SCHEMBL341318 | 0.77 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL9924111 | 0.77 | NOS3 (0.31) | — | |
| SCHEMBL342302 | 0.75 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL15541721 | 0.75 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL9957528 | 0.74 | HTT (0.40) | — | |
| SCHEMBL9957046 | 0.74 | POLB (0.38) | — | |
| SCHEMBL9372265 | 0.72 | HSD17B10 (0.40) | — | |
| SCHEMBL342075 | 0.72 | SMN1; SMN2 (0.40) | — | |
| SCHEMBL20531089 | 0.72 | GAA (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007067537-A1 | PYRROLOPYRIDINE KINASE INHIBITING COMPOUNDS | OSI PHARMACEUTICALS, INC. (US) | 2007-06-14 | — | — | WO | disclosed |