SCHEMBL342075

SCHEMBL342075

CC(C)(C=O)CN1CCOCC1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.40
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
GAA P10253 1/20 0.37
SIGMAR1 Q99720 1/20 0.37
KDM4E B2RXH2 4/20 0.36
HSD17B10 Q99714 2/20 0.36
ALDH1A1 P00352 3/20 0.36
RECQL P46063 1/20 0.36
ALOX15 P16050 1/20 0.35
TSHR P16473 1/20 0.35
USP2 O75604 1/20 0.34
GLA P06280 1/20 0.34
LMNA P02545 1/20 0.34
KEAP1 Q14145 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2420027 0.84
SCHEMBL341318 0.80 SMN1; SMN2 (0.34) SMN1; SMN2SIGMAR1KDM4EHSD17B10ALDH1A1
SCHEMBL12463624 0.80 MEN1 (0.50) SMN1; SMN2MEN1KMT2ASIGMAR1KDM4E
SCHEMBL342302 0.78 SMN1; SMN2 (0.38) SMN1; SMN2GAASIGMAR1HSD17B10ALDH1A1
SCHEMBL15541721 0.78 SMN1; SMN2 (0.38) SMN1; SMN2GAASIGMAR1HSD17B10ALDH1A1
SCHEMBL9957046 0.77 POLB (0.38) SMN1; SMN2MEN1KMT2AKDM4EALDH1A1
SCHEMBL9957528 0.77 HTT (0.40) SIGMAR1KDM4EALDH1A1RECQLALOX15
SCHEMBL17392772 0.76 SMN1; SMN2 (0.43) SMN1; SMN2MEN1KMT2AGAASIGMAR1
SCHEMBL19971101 0.75 SIGMAR1 (0.39) SMN1; SMN2MEN1KMT2ASIGMAR1ALDH1A1
SCHEMBL20531089 0.75 GAA (0.35) GAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 278 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2651876-B1 POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS SIKA TECH AG (CH) 2017-08-09 EP claimed
CN-102648230-B The extremely low low viscosity epoxy resin compositions of blushing SIKA技术股份公司 2017-03-01 CN claimed
CN-103313995-B Secondary aminosilanes SIKA技术股份公司 2016-08-10 CN claimed
CN-103261146-B Polyamines having secondary aliphatic amino groups SIKA TECHNOLOGY AG (CH) 2016-01-27 CN claimed
US-8877955-B2 Secondary aminosilanes SIKA TECHNOLOGY AG (CH) 2014-11-04 US claimed
US-8703844-B2 Low-viscosity epoxy resin composition with low blushing SIKA TECHNOLOGY AG (CH) 2014-04-22 US claimed
US-20130281562-A1 SECONDARY AMINOSILANES SIKA TECHNOLOGY AG (CH) 2013-10-24 US claimed
EP-2651876-A1 POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS Sika Technology AG (CH) 2013-10-23 EP claimed
EP-2651956-A1 SECONDARY AMINOSILANES Sika Technology AG (CH) 2013-10-23 EP claimed
US-20130261270-A1 POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS SIKA TECHNOLOGY AG (CH) 2013-10-03 US claimed
CN-103261146-A Polyamines having secondary aliphatic amino groups SIKA TECHNOLOGY AG 2013-08-21 CN claimed
US-20120270967-A1 LOW-VISCOSITY EPOXY RESIN COMPOSITION WITH LOW BLUSHING SIKA TECHNOLOGY AG (CH) 2012-10-25 US claimed
CN-102648230-A Low-viscosity epoxy resin composition with low blushing SIKA TECHNOLOGY AG 2012-08-22 CN claimed
EP-2336213-B1 Low viscosity epoxide resin compound with low blushing SIKA TECHNOLOGY AG (CH) 2012-08-01 EP claimed
EP-2468759-A1 Secondary Aminosilanes Sika Technology AG (CH) 2012-06-27 EP claimed
WO-2012080266-A1 SECONDARY AMINOSILANES SIKA TECHNOLOGY AG (CH) 2012-06-21 WO claimed
WO-2012080265-A1 POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS SIKA TECHNOLOGY AG (CH) 2012-06-21 WO claimed
EP-2465843-A1 Polyamines with secondary aliphatic amines Sika Technology AG (CH) 2012-06-20 EP claimed
EP-2336213-A1 Low viscosity epoxide resin compound with low blushing Sika Technology AG (CH) 2011-06-22 EP claimed
WO-2011069846-A1 LOW-VISCOSITY EPOXY RESIN COMPOSITION WITH LOW BLUSHING SIKA TECHNOLOGY AG (CH) 2011-06-16 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130281562-A1 SECONDARY AMINOSILANES AS3MT, SRM, MSN SMN1; SMN2 542/4885MEN1 2889/4885KMT2A 293/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.