Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.33 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15541721 | 1.00 | SMN1; SMN2 (0.38) | SMN1; SMN2TSHRHSD17B10ALDH1A1SIGMAR1 | |
| SCHEMBL341318 | 0.98 | SMN1; SMN2 (0.34) | SMN1; SMN2TSHRHSD17B10ALDH1A1SIGMAR1 | |
| Piperazine SCHEMBL28078125 | 0.90 | SMN1; SMN2 (0.33) | SMN1; SMN2TSHRHSD17B10ALDH1A1 | |
| SCHEMBL2420027 | 0.88 | — | — | |
| SCHEMBL9957046 | 0.80 | POLB (0.38) | SMN1; SMN2ALDH1A1MAPTHRH3POLB | |
| SCHEMBL9957528 | 0.80 | HTT (0.40) | ALDH1A1SIGMAR1MAPTHPGD | |
| SCHEMBL12156734 | 0.79 | HRH3 (0.41) | SMN1; SMN2TSHRALDH1A1HRH3 | |
| SCHEMBL19971101 | 0.78 | SIGMAR1 (0.39) | SMN1; SMN2ALDH1A1SIGMAR1MAPTHPGD | |
| SCHEMBL20531089 | 0.78 | GAA (0.35) | ALDH1A1GAAPOLB | |
| SCHEMBL342075 | 0.78 | SMN1; SMN2 (0.40) | SMN1; SMN2TSHRHSD17B10ALDH1A1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651876-B1 | POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | SIKA TECH AG (CH) | 2017-08-09 | — | — | EP | claimed |
| CN-103313995-B | Secondary aminosilanes | SIKA技术股份公司 | 2016-08-10 | — | — | CN | claimed |
| CN-103261146-B | Polyamines having secondary aliphatic amino groups | SIKA TECHNOLOGY AG (CH) | 2016-01-27 | — | — | CN | claimed |
| US-8877955-B2 | Secondary aminosilanes | SIKA TECHNOLOGY AG (CH) | 2014-11-04 | — | — | US | claimed |
| US-20130281562-A1 | SECONDARY AMINOSILANES | SIKA TECHNOLOGY AG (CH) | 2013-10-24 | — | — | US | claimed |
| EP-2651956-A1 | SECONDARY AMINOSILANES | Sika Technology AG (CH) | 2013-10-23 | — | — | EP | claimed |
| EP-2651876-A1 | POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | Sika Technology AG (CH) | 2013-10-23 | — | — | EP | claimed |
| US-20130261270-A1 | POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | SIKA TECHNOLOGY AG (CH) | 2013-10-03 | — | — | US | claimed |
| CN-103313995-A | Secondary aminosilanes | SIKA TECHNOLOGY AG | 2013-09-18 | — | — | CN | claimed |
| CN-103261146-A | Polyamines having secondary aliphatic amino groups | SIKA TECHNOLOGY AG | 2013-08-21 | — | — | CN | claimed |
| EP-2468759-A1 | Secondary Aminosilanes | Sika Technology AG (CH) | 2012-06-27 | — | — | EP | claimed |
| WO-2012080266-A1 | SECONDARY AMINOSILANES | SIKA TECHNOLOGY AG (CH) | 2012-06-21 | — | — | WO | claimed |
| WO-2012080265-A1 | POLYAMINES HAVING SECONDARY ALIPHATIC AMINO GROUPS | SIKA TECHNOLOGY AG (CH) | 2012-06-21 | — | — | WO | claimed |
| EP-2465843-A1 | Polyamines with secondary aliphatic amines | Sika Technology AG (CH) | 2012-06-20 | — | — | EP | claimed |
| EP-3484898-B1 | METHOD OF STABILIZING IMINO-FUNCTIONAL SILANE | MOMENTIVE PERFORMANCE MAT INC (US) | 2023-06-28 | — | — | EP | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| CN-109563111-B | Method for stabilizing imino-functional silanes | 莫门蒂夫性能材料股份有限公司 | 2022-04-12 | — | — | CN | disclosed |
| EP-0236140-A2 | Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-09-09 | — | — | EP | disclosed |
| US-4125530-A | FROM 1,1-DIHALO-3,3,3-TRIFLUOROACETONE, BASE, AMMONIA AND A CARBOXALDEHYDE | MERCK & CO., INC. (US) | 1978-11-14 | — | — | US | disclosed |
| US-4032522-A | ANTI-GOUT, ANTI-HYPERURICEMIC | MERCK & CO., INC. (US) | 1977-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281562-A1 | SECONDARY AMINOSILANES | AS3MT, SRM, MSN | SMN1; SMN2 542/4885TSHR 4730/4885HSD17B10 4207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.