Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 17/20 | 0.43 |
| ▸ | CDK9 | P50750 | 17/20 | 0.43 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14531051 | 0.91 | CCNT1 (0.40) | CCNT1CDK9PRKCQEGFR | |
| SCHEMBL14530722 | 0.90 | EGFR (0.39) | CCNT1CDK9PRKCQEGFR | |
| SCHEMBL14500618 | 0.90 | CCNT1 (0.40) | CCNT1CDK9PRKCQ | |
| SCHEMBL14500619 | 0.89 | CDK9 (0.48) | CCNT1CDK9PRKCQ | |
| SCHEMBL14500614 | 0.82 | CCNT1 (0.47) | CCNT1CDK9 | |
| SCHEMBL14520510 | 0.82 | CDK9 (0.48) | CCNT1CDK9PRKCQ | |
| SCHEMBL14530589 | 0.80 | CCNT1 (0.40) | CCNT1CDK9EGFR | |
| SCHEMBL14530588 | 0.80 | EGFR (0.39) | CCNT1CDK9EGFR | |
| SCHEMBL14500616 | 0.79 | CCNT1 (0.40) | CCNT1CDK9 | |
| SCHEMBL13994232 | 0.79 | TBK1 (0.51) | CCNT1CDK9PRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007067537-A1 | PYRROLOPYRIDINE KINASE INHIBITING COMPOUNDS | OSI PHARMACEUTICALS, INC. (US) | 2007-06-14 | — | — | WO | disclosed |