SCHEMBL14520586

CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C=O)C(C)C

nearest known ligand 0.60

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	NPY4R	P50391	15/20	0.60

▸	NPY1R	P25929	9/20	0.60

▸	NPY5R	Q15761	8/20	0.60

▸	NPY2R	P49146	5/20	0.60

▸	KISS1R	Q969F8	4/20	0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL13367326	1.00	NPY4R (0.60)	NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL30656950	0.88	NPY4R (0.68)	NPY4RNPY1RNPY5RNPY2R
SCHEMBL30656922	0.88	NPY4R (0.68)	NPY4RNPY1RNPY5RNPY2R
SCHEMBL31332245	0.83	NPY4R (0.55)	NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL29376517	0.82	NPY4R (0.64)	NPY4RNPY1RNPY5RNPY2R
SCHEMBL30174990	0.82	NPY4R (0.58)	NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL31388270	0.82	NPY4R (0.64)	NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL30895760	0.82	NPY4R (0.58)	NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL30285520	0.82	NPY4R (0.58)	NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL16508584	0.81	NPY4R (0.66)	NPY4RNPY1RNPY5RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2007065808-A2	NEUROPEPTIDE-2 RECEPTOR-AGONISTS	F. HOFFMANN-LA ROCHE AG (CH)	2007-06-14	—	—	WO	disclosed